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after reconstitution, refrigerate at 28 C (35.646.4 F)

Neuropathological and imaging studies report macrostructural and microstructural brain differences, including reduced Purkinje cells (Johnson et al., 2007), neocortical anomalies, macrocephaly in early life, and altered trophic signaling, all consistent with atypical neurodevelopmental trajectories (Courchesne et al., 2001